Gusuzuma Serologiya Indwara Yamaboko, Ikirenge, n umunwa

Indwara y'intoki, ikirenge, n'umunwa (HFMD) Incamake

Indwara y'intoki, ikirenge, n'umunwa yiganje cyane cyane mubana bato. Yanduye cyane, ifite umubare munini wubwandu bwa simptomatic, inzira zanduza zanduye, hamwe no gukwirakwira vuba, birashobora gutera indwara mugihe gito, bigatuma kurwanya icyorezo bitoroshye. Mugihe cyadutse, indwara zandurira mu mashuri y'incuke no mu bigo byita ku bana, hamwe no guhurira hamwe mu miryango. Muri 2008, HFMD yashyizwe muri Minisiteri y’ubuzima mu micungire y’indwara zandura zo mu cyiciro C.

Coxsackievirus A16 (CA16) na Enterovirus 71 (EV71) ni virusi zisanzwe zitera HFMD. Icyorezo cya Epidemiologiya cyerekana ko CA16 ikwirakwizwa icyarimwe na EV71, bigatuma HFMD ikunda kwibasira. Muri ibi byorezo, umubare w'abanduye CA16 urenze kure uwa EV71, akenshi ukaba urenga 60% byanduye. HFMD iterwa na EV71 irashobora gutuma sisitemu yo hagati yangirika. Umubare w'abantu bakabije ndetse n'abapfa bapfa mu barwayi banduye EV71 uri hejuru cyane ugereranije n'abanduye izindi enterovirusi, aho abapfa bapfa bagera kuri 10% -25%. Nyamara, ubwandu bwa CA16 muri rusange ntabwo butera indwara zinyuranye zifata imitsi nka sisitemu ya meningite nka aseptic meningitis, ubwonko bwa encephalitis, hamwe na paraliyelite isa na paralize. Kubwibyo, kwisuzumisha hakiri kare ni ngombwa cyane kurokora ubuzima bwimanza zikomeye.

Kwipimisha kwa Clinical

Igeragezwa rya kliniki ya HFMD ririmo cyane cyane nucleic acide ya patogene na serologiya antibody. Isosiyete ya Beier ikoresha enzyme ihujwe na immunosorbent assay (ELISA) hamwe nuburyo bwa zahabu bwa colloidal mugutezimbere Enterovirus 71 Ibikoresho byo Kwipimisha Antibody na Coxsackievirus A16 IgM Antibody Test Kits kugirango hamenyekane itandukaniro rya virusi ya HFMD. Indwara ya antibody ya serumu itanga ibyiyumvo bihanitse, umwihariko, kandi biroroshye, byihuse, kandi birakwiriye kwipimisha kwa muganga mubigo nderabuzima mu nzego zose ndetse n’ubushakashatsi bunini bwo gukurikirana epidemiologiya.

Ibipimo byihariye byo kwisuzumisha hamwe nubuvuzi bwa Clinical akamaro ko kwandura EV71

Isuzuma ryihariye ryanduye rya EV71 rishingiye ku kumenya antibodiyite za EV71-RNA, EV71-IgM, na EV71-IgG muri serumu, cyangwa kumenya EV71-RNA mu ngero za swab.

Nyuma yo kwandura EV71, antibodies za IgM zigaragara mbere, zikagera mucyumweru cya kabiri. Antibodies za IgG zitangira kugaragara mucyumweru cya kabiri nyuma yo kwandura kandi zigakomeza igihe kirekire. EV71-IgM nikimenyetso cyingenzi cyubwandu bwibanze cyangwa bwa vuba, byorohereza gutahura hakiri kare no kuvura indwara ya EV71. EV71-IgG ni ikimenyetso cyingenzi cyo gusuzuma itandukaniro ryanduye, rifite akamaro mu iperereza ry’ibyorezo no gusuzuma ingaruka z’inkingo. Kumenya ihinduka rya antibody ya titer hagati ya serumu ikaze na convalescent ya serumu irashobora kandi kumenya imiterere ya virusi ya EV71; kurugero, kwiyongera inshuro enye cyangwa nini cyane ya geometrike muri antibody titer muri serumu ya convalescent ugereranije na serumu ikaze irashobora gufatwa nkubwandu bwa EV71.

Ibipimo byihariye byo kwisuzumisha hamwe n'akamaro ka Clinical yo kwandura CA16

Isuzuma ryihariye ryanduye CA16 rishingiye ku kumenya antibodiyite za CA16-RNA, CA16-IgM, na CA16-IgG muri serumu, cyangwa kumenya CA16-RNA mu ngero za swab.

Nyuma yo kwandura CA16, antibodies za IgM zigaragara mbere, zikagera mucyumweru cya kabiri. Antibodies za IgG zitangira kugaragara mucyumweru cya kabiri nyuma yo kwandura kandi zigakomeza igihe kirekire. CA16-IgM nikimenyetso cyingenzi cyubwandu bwibanze cyangwa bwa vuba.

Akamaro ka EV71 hamwe na CA16 Kwipimisha Antibody

HFMD iterwa na enterovirus nyinshi, hamwe na serotypes zisanzwe ari EV71 na CA16. Ubushakashatsi bwerekana ko HFMD iterwa na virusi ya CA16 mubisanzwe igaragaza ibimenyetso bya kera, ifite ibibazo bike, hamwe no gutangaza neza. Ibinyuranye na byo, HFMD iterwa na EV71 ikunze kwerekana ibimenyetso bikomeye by’amavuriro, ikagira umubare munini w’indwara zikomeye n’impfu, kandi akenshi ikaba ifitanye isano n’ibibazo biterwa na sisitemu yo hagati. Ibimenyetso bya clinique ya HFMD biragoye kandi akenshi ntibisanzwe, bigatuma kwisuzumisha kwa clinique bigoye cyane cyane mugihe cyambere. Akamaro ko gupima antibody ya serumu ihuriweho ni ugusimbuza uburyo bwa virusi itwara igihe kandi bitoroshye, gutandukanya virusi ya serologiya, no gutanga ishingiro ryo gusuzuma amavuriro, ingamba zo kuvura, no gutangaza indwara.

Isesengura ry'ibicuruzwa

EV71-IgM ELISAKitIsesengura ry'imikorere

Ibisubizo byerekana:Ikizamini cya Beier EV71-IgM cyerekana ibyiyumvo bihanitse kandi byihariye byo gupima serumu kubantu banduye EV71. Inkomoko yamakuru: Ikigo cyigihugu gishinzwe kurwanya no gukumira virusi, CDC yo mu Bushinwa.

EV71-IgG ELISA Isesengura ryimikorere ya Kit (I)

EV71-IgG ELISA Isesengura ryimikorere ya Kit (II)

Ibisubizo byerekana:Ikizamini cya Beier EV71-IgG cyerekana igipimo kinini cyo kumenya serumu kubantu banduye EV71. Inkomoko yamakuru: Ikigo cyigihugu gishinzwe kurwanya no gukumira virusi, CDC yo mu Bushinwa.

CA16-IgM ELISA Isesengura ryimikorere ya Kit

Ibisubizo byerekana:Ikizamini cya Beier CA16-IgM cyerekana igipimo cyo hejuru cyo kumenya no guhuza neza. Inkomoko yamakuru: Ikigo cyigihugu gishinzwe kurwanya no gukumira virusi, CDC yo mu Bushinwa.

Isesengura ryimikorere ya EV71-IgM (Zahabu ya Colloidal) Isesengura ryimikorere

Ibisubizo byerekana:Ikizamini cya Beier EV71-IgM (Zahabu ya Colloidal) yerekana ibyiyumvo bihanitse kandi byihariye byo gupima serumu kubantu banduye EV71. Inkomoko yamakuru: Ikigo cyigihugu gishinzwe kurwanya no gukumira virusi, CDC yo mu Bushinwa.

Isesengura ryimikorere ya CA16-IgM (Zahabu ya Colloidal) Isesengura ryimikorere

Ibisubizo byerekana:Ikizamini cya Beier CA16-IgM (Zahabu ya Colloidal) yerekana ibyiyumvo bihanitse kandi byihariye byo kumenya serumu kubantu banduye CA16. Inkomoko yamakuru: Ikigo cyigihugu gishinzwe kurwanya no gukumira virusi, CDC yo mu Bushinwa.