Kanseri ya Nasopharyngeal (nay-zoh-fuh-RIN-jee-ul) kanseri ni kanseri igaragara muri nasofarynx, iri inyuma yizuru kandi hejuru yinyuma yumuhogo wawe.
Kanseri ya Nasopharyngeal ni gake muri Amerika.Biboneka cyane mubindi bice byisi - cyane cyane Aziya yepfo yepfo.
Kanseri ya Nasopharyngeal iragoye kuyimenya hakiri kare.Ibyo birashoboka ko kuberako nasofarynx itoroshye kuyisuzuma nibimenyetso bya kanseri ya nasofaryngeal yigana iyindi, ibintu bisanzwe.
Kanseri ya Nasopharyngeal iboneka cyane cyane mu bageze mu za bukuru ndetse no mu zabukuru barengeje imyaka 40, kandi ifite ibimenyetso bigaragara mu karere ndetse no mu miryango, kandi umubare w'abanduye i Guangdong uri ku mwanya wa mbere mu Bushinwa, uzwi kandi ku izina rya "Kanseri ya Guangdong".
1.Amabwiriza yo gusuzuma no kuvura kanseri ya Nasofaryngeal
Mu Mabwiriza yo mu 2021 agamije gusuzuma no kuvura kanseri ya Nasopharyngeal, Umuryango w’Abashinwa w’Ubuvuzi bwa Oncologiya (CSCO) washyizemo uburyo bwo gutahura serologiya mu kimenyetso cya mbere cyo gusuzuma kanseri ya nasofaryngeal, anagaragaza ko guhuza EB-VCA-IgA na EB-NA1-IgA antibodiyite EB-virusi irashobora kongera igipimo cyo gusuzuma hakiri kare kanseri ya nasofaryngeal inshuro 3 (21% ~ 79%) kandi bikagabanya ibyago byo gupfa 88%!Impuguke z’impuguke za 2019 ku bijyanye n’ubuvuzi bwa Markers kuri Nasopharyngeal Carcinoma nazo zagaragaje ko EBV-EA-IgA ari ikimenyetso cy’indwara ya EBV iheruka cyangwa ikwirakwizwa rya EBV, ifite urwego rwihariye, kandi ikoreshwa kenshi mu gusuzuma kanseri ya nasofaryngeal no kwisuzumisha hakiri kare.
Ubushakashatsi bwerekana ko ibintu bitatu byahujwe na EBV-VCA-IGA, EBV-EA-IGA na EB-NA1-IgA bikubiyemo neza imiterere ya gene ya EBV, ibyo bikaba binonosora neza ibyiyumvo byihariye n’umwihariko wo kumenya kanseri ya nasofaryngeal, bikagabanya gutahura neza, bikabuza ko ubunyangamugayo bwo guhanura indwara, kandi bugahanura ko hashobora kubaho indwara imyaka 5-10 mbere, ikaba ikwiriye kwipimisha kanseri nini ya nasofaryngeal.
2. VCA-IgA + EA-IgA + NA1-IgA yakozwe na Beijing Beier irashobora gutanga protocole yo gusuzuma hakiri kare kanseri ya Nasopharyngeal.
Magnetism igabanya immuno chemistry luminescence uburyo
| izina RY'IGICURUZWA | Amagambo ahinnye |
| EB virusi VCA-IgA igikoresho cyo kumenya antibody | EB-VCA-IgA |
| EB virusi EA-IgA igikoresho cyo kumenya antibody | EB-EA-IgA |
| EB virusi NA1-IgA igikoresho cyo kumenya antibody | EB-NA1-IgA |
Uburyo bwa Elisa:
| izina RY'IGICURUZWA | Amagambo ahinnye |
| EB virusi VCA-IgA Elisa kit | EB-VCA-IgA |
| EB virusi EA-IgA Elisa kit | EB-EA-IgA |
| EB virusi NA1-IgA Elisa kit | EB-NA1-IgA |
3.Imikorere y'ibicuruzwa
Ikizamini cya VCA-IgA cyakozwe na Beijing Beier kirashobora gusimbuza ibikoresho by’ubumwe bw’ibihugu by’Uburayi kugira ngo bimenyekane hakiri kare no gusuzuma kanseri ya nasofaryngeal.
Ikinyamakuru cy’ubuvuzi cyo mu Bwongereza (BMJ) (ingaruka 16.378) ni kimwe mu binyamakuru bine by’ubuvuzi ku isi.Muri 2017, itsinda ry’ubushakashatsi ryasohoye urupapuro mu kinyamakuru cy’ubuvuzi cy’Ubwongereza (BMJ) "Isuzuma ry’ibikoresho birindwi bya recombinant VCA-IgA ELISA byo gusuzuma kanseri ya nasofaryngeal mu Bushinwa: iburanisha rishinzwe kugenzura imanza".
Muri iyi nyandiko, abarwayi 200 barwaye kanseri ya nasofaryngeal (NPC) hamwe na 200 zisanzwe za serumu zabantu (SYSUCC) zo mu kigo cya kanseri cya kaminuza ya Sun Yat-sen zakozwe kandi zipimwa, ndetse n’imikorere y’ibikoresho bya EB-VCA-IgA (ELISA) byakozwe na 8 abakora ibicuruzwa ku isoko ryimbere mu gihugu bagereranijwe no gusuzuma imikorere.Umwanzuro nuko ibikoresho bya EBV-VCA-IgA (ELISA) byakozwe na Beijing Beier bifite ingaruka zimwe zo gusuzuma nka EBV-VCA-IgA (ELISA) byakozwe na Oumeng reagent yatumijwe mu mahanga, na EBV-VCA-IgA (ELISA) ibikoresho byakozwe na Beijing Beier birashobora gusimbuza ibikoresho byatumijwe hanze kugirango hamenyekane hakiri kare no gusuzuma kanseri ya nasofaryngeal.Ibisobanuro by'abakora ibicuruzwa bitabiriye ikizamini bigaragara mu mbonerahamwe ya 1, ibisubizo by'ibizamini bigaragara mu mbonerahamwe ya 2, naho imyanzuro y'ibizamini igaragara mu mbonerahamwe ya 3.
Umwanzuro w'ikizamini
Ibintu bitatu bya recombinant VCA-IgA kits-BB, HA na KSB- byagize ingaruka zo kwisuzumisha zingana nibisanzwe mubikoresho bisanzwe.Bishobora gusimburwa nibikoresho bisanzwe kandi guhuza kwabo bishobora gukoreshwa mugutahura hakiri kare no gusuzuma NPC.
Igihe cyo kohereza: Gashyantare-23-2023